Polymyxin B Sulfate

(HB0530)

Product overview

  • Name
    Polymyxin B Sulfate
  • Short description
    Cationic antimicrobial peptide
  • Biological description
    Cationic antimicrobial peptide. Mixture of polymyxin components such as B1 and B2. Displays high affinity for lipopolysaccharide (LPS) and causes LPS aggregation. Shows bactericidal antibiotic actions against gram-negative bacteria.
  • Biological action
    Antibiotic
  • Our products in action

Properties

  • Chemical name
    Aerosporin
  • Molecular Weight
    1385.6
  • Molecular Formula
    C55H96N16O13.2H2SO4
  • CAS Number
    1405-20-5

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Solubility overview
    soluble in water (50mg/ml)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Polymyxin B Sulfate

  • In vitro potency of various polymyxin B components.

    Tam VH et al (2011) Antimicrob Agents Chemother 55(9) : 4490-1.
    PubMedID: 21709096
  • Enzymatic modification of lipid A by ArnT protects Bordetella bronchiseptica against cationic peptides and is required for transmission.

    Rolin O et al (2014) Infect Immun 82(2) : 491-9.
    PubMedID: 24478065
  • Biophysical characterization of polymyxin B interaction with LPS aggregates and membrane model systems.

    Domingues MM et al (2012) Biopolymers 98(4) : 338-44.
    PubMedID: 23193598

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