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Product overview

  • Name
    PP 3
  • Short description
    PP 2 negative control
  • Biological description
    PP 2 (Src kinase inhibitor) negative control. Does not inhibit Src family kinases. Inhibits EGFR kinase and CK1δ (IC50 values are 2.7 and 9.9 µM respectively).
  • Biological action
  • Purity
  • Citations


  • Chemical name
  • Molecular Weight
  • Molecular Formula
  • CAS Number

Storing and Using Your Product

  • Storage instructions
  • Solubility overview
    soluble in DMSO (100mM) or ethanol (25mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for PP 3

  • Src family kinase inhibitor PP2 efficiently inhibits cervical cancer cell proliferation through down-regulating phospho-Src-Y416 and phospho-EGFR-Y1173.

    Kong L et al (2011) Mol Cell Biochem 348(1-2) : 11-9.
    PubMedID: 21052789
  • The specificities of protein kinase inhibitors: an update.

    Bain J et al (2003) Biochem J 371(Pt 1) : 199-204.
    PubMedID: 12534346
  • Use of a pharmacophore model for the design of EGF-R tyrosine kinase inhibitors: 4-(phenylamino)pyrazolo[3,4-d]pyrimidines.

    Traxler P et al (1997) J Med Chem 40(22) : 3601-16.
    PubMedID: 9357527
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