Target

Synthetic estrogen receptor ligand. Widely used in genome engineering (e.g. CreER/ CRISPR-Cas9).

Estrogen receptor ligand. For inducible genome manipulation (e.g. Cre-LoxP (CreER)/ TRAP/ CRISPR-Cas9).

K_v7.4 channel activator

Synthetic PKC activator

Piezo1 channel activator

Novel, selective Piezo1 channel activator. Improved efficacy and potency compared to Yoda1.

LKB1/AMPK activator. Also promotes neurogenesis.

mTOR activator and autophagy inhibitor. Cell-permeable.

K_ir6 channel activator

Selective K_v7.2 / K_v7.4 channel activator