Novel tool for studying GPCR desensitization
An exclusive from Hello Bio, Cmpd101 is a novel, potent, selective G-protein coupled receptor kinase 2 and 3 inhibitor (IC50 values are 35, 290 nM and 125 µM at GRK2, GRK3 and GRK5 respectively). Selective over other kinases. Can be used to study roles of GRK2/3 in GPCR desensitization...Read more
Kainate receptors are members of the ionotropic class of glutamate receptors and consist of GluK1 (formerly GluR5), GluK2 (formerly GluR6), GluK3 (formerly GluR7), GluK4 (formerly KA1) and GluK5 (formerly KA2) subunits. Researchers can save 50% on kainate receptor agonists and antagonists from Hello Bio - they are up to half the price of other suppliers.