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G protein coupled receptors

G-protein-coupled receptors (also known as GPCRs, transmembrane receptors, or 7-TM receptors), are integral membrane proteins that contain seven membrane-spanning domains (helices). They are coupled to heterotrimeric G proteins on the intracellular side of the cell membrane. Ligand binding causes a conformational change in the GPCR, that is then transmitted to the G protein, activating a signal transduction pathway. GPCRs include acetycholine muscarinic, adenosine, GABAB, and histamine receptors, and the metabotropic glutamate receptors (Group I, Group II and Group III). Researchers can save up to 50% on GPCR receptor agonists, antagonists and allosteric modulators from Hello Bio - they are up to half the price of other suppliers.

  1. 6-Hydroxydopamine (6-OHDA) hydrobromide
    Reviews:
    Description:

    Neurotoxin, widely used to produce the 6-OHDA Parkinson’s disease model

    Purity :

    >98%

    Pack: Price: Qty:
    50mg
    $43
    250mg
    $82
    1g
    $273
  2. Description:

    Potent dopamine D4 receptor partial agonist

    Purity :

    >99%

    Pack: Price: Qty:
    50mg
    $456
  3. Amisulpride(HB1879)

    Description:

    Potent, selective dopamine D2 and D3 receptor antagonist. Atypical antipsychotic.

    Purity :

    >98%

    Pack: Price: Qty:
    50mg
    $98
  4. Bromocriptine mesylate
    Description:

    Potent, selective D2-like receptor agonist

    Purity :

    >98%

    Pack: Price: Qty:
    50mg
    $94
  5. CA200773 CellAura fluorescent D1 antagonist [SKF83566-green]
    Description:

    Fluorescent D1 dopamine receptor antagonist

    Pack: Price: Qty:
    50μg
    $195
  6. Clozapine

    Clozapine(HB1607)

    Reviews:
    Description:

    Prototypic, atypical antipsychotic, binds to both serotonin and dopamine receptors

    Purity :

    >99%

    Pack: Price: Qty:
    50mg
    $84
    500mg
    $354
  7. Clozapine dihydrochloride (water soluble)
    Reviews:
    Description:

    Water soluble prototypic, atypical antipsychotic. Binds to both serotonin and dopamine receptors.

    Purity :

    >98%

    Pack: Price: Qty:
    10mg
    $38
    50mg
    $99
  8. Description:

    5-HT antagonist. Also partial agonist at adrenergic and dopaminergic receptors.

    Purity :

    >98%

    Pack: Price: Qty:
    100mg
    $82
  9. Domperidone(HB1888)

    Description:

    Peripheral dopamine D2-like receptor antagonist

    Purity :

    >99%

    Pack: Price: Qty:
    50mg
    $65
  10. Description:

    Fluorimetric reagent. Catecholamine metabolite.

    Purity :

    >99%

    Pack: Price: Qty:
    50mg
    $49