Novel tool for studying GPCR desensitization
An exclusive from Hello Bio, Cmpd101 is a novel, potent, selective G-protein coupled receptor kinase 2 and 3 inhibitor (IC50 values are 35, 290 nM and 125 µM at GRK2, GRK3 and GRK5 respectively). Selective over other kinases. Can be used to study roles of GRK2/3 in GPCR desensitization...Read more
Adenosine receptors are G-protein coupled receptors, activated by the endogenous nucleoside adenosine, and classified into A1, A2A, A2B and A3 receptors. These adenosine receptors are also referred to as P1 receptors to distinguish them from the receptors for nucleotides (P2X and P2Y receptors). Researchers can save up to 50% on adenosine (P1) receptor agonists, antagonists, modulators and fluorescent ligands from Hello Bio - they are up to half the price of other suppliers.