DREADD

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Designer receptors exclusively activated by designer drugs (DREADDs) are genetically engineered GPCRs that are activated by physiologically inert synthetic small molecules (designer drugs) but not their endogenous ligand. Read our DREADDs mini-review or for practical advice on using these ligands in the lab see Stability of Water-Soluble DREADD Ligands in Solution: A Technical Review and Clozapine N-Oxide (freebase) - a technical review on stability, solubility and use in the lab).

Items 1-10 of 20

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  1. Clozapine (HB1607)

    1  Review
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    Description:

    Prototypic, atypical antipsychotic, binds to both serotonin and dopamine receptors

    Purity:

    >99%

    Pack:
    5mg
    Price:
    $20
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    Pack:
    10mg
    Price:
    $28
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    Pack:
    25mg
    Price:
    $55
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    Pack:
    50mg
    Price:
    $88
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    Pack:
    100mg
    Price:
    $132
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    Pack:
    500mg
    Price:
    $476
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  2. 3  Reviews
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    Description:

    Water soluble prototypic, atypical antipsychotic. Binds to both serotonin and dopamine receptors.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $33
    Qty:
    Pack:
    10mg
    Price:
    $53
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    Pack:
    25mg
    Price:
    $99
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    Pack:
    50mg
    Price:
    $141
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    Pack:
    100mg
    Price:
    $198
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  3. Pack:
    5mg
    Price:
    $96
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    Pack:
    10mg
    Price:
    $138
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    Pack:
    25mg
    Price:
    $310
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    Pack:
    50mg
    Price:
    $573
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    Pack:
    100mg
    Price:
    $934
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    Pack:
    5mg (10mM in water)
    Price:
    $107
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  4. Pack:
    5mg
    Price:
    $73
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    Pack:
    10mg
    Price:
    $108
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    Pack:
    25mg
    Price:
    $261
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    Pack:
    50mg
    Price:
    $447
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    Pack:
    100mg
    Price:
    $847
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  5. 1  Review
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    Description:

    Potent, selective and metabolically stable hM3Dq and hM4Di muscarinic DREADD actuator.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $58
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    Pack:
    10mg
    Price:
    $90
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    Pack:
    25mg
    Price:
    $195
    Qty:
    Pack:
    50mg
    Price:
    $316
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    Pack:
    100mg
    Price:
    $495
    Qty:
  6. 11  Reviews
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    Description:

    Potent, selective and metabolically stable hM3Dq and hM4Di muscarinic DREADD actuator. Water soluble.

    Purity:

    >99%

    Pack:
    5mg
    Price:
    $63
    Qty:
    Pack:
    10mg
    Price:
    $108
    Qty:
    Pack:
    25mg
    Price:
    $216
    Qty:
    Pack:
    50mg
    Price:
    $351
    Qty:
    Pack:
    100mg
    Price:
    $522
    Qty:
  7. 25  Reviews
    Top Reviews:
    99% of 100
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    Description:

    Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Brain penetrant. Water soluble.

    Purity:

    >98%

    Pack:
    1mg
    Price:
    $33
    Qty:
    Pack:
    5mg
    Price:
    $88
    Qty:
    Pack:
    10mg
    Price:
    $157
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    Pack:
    25mg
    Price:
    $361
    Qty:
    Pack:
    50mg
    Price:
    $583
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    Pack:
    100mg
    Price:
    $1,045
    Qty:
  8. 1  Review
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    100% of 100
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    Description:

    Effective agonist for muscarinic-based DREADDs in vitro and in vivo. Non-CNO chemogenetic actuator. Brain penetrant.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $114
    Qty:
    Pack:
    10mg
    Price:
    $172
    Qty:
    Pack:
    25mg
    Price:
    $366
    Qty:
    Pack:
    50mg
    Price:
    $650
    Qty:
    Pack:
    100mg
    Price:
    $1,174
    Qty:
  9. Description:

    Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Freebase.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $102
    Qty:
    Pack:
    10mg
    Price:
    $199
    Qty:
    Pack:
    25mg
    Price:
    $420
    Qty:
    Pack:
    100mg
    Price:
    $1,099
    Qty:
  10. Description:

    Novel DREADD agonist with high affinity and potency for hM3Dq and hM4Di. Active in vivo. Water soluble.

    Purity:

    >98%

    Pack:
    5mg
    Price:
    $102
    Qty:
    Pack:
    10mg
    Price:
    $199
    Qty:
    Pack:
    25mg
    Price:
    $420
    Qty:
    Pack:
    100mg
    Price:
    $1,548
    Qty:
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