Novel tool for studying GPCR desensitization
An exclusive from Hello Bio, Cmpd101 is a novel, potent, selective G-protein coupled receptor kinase 2 and 3 inhibitor (IC50 values are 35, 290 nM and 125 µM at GRK2, GRK3 and GRK5 respectively). Selective over other kinases. Can be used to study roles of GRK2/3 in GPCR desensitization...Read more
Histamine receptors are G-protein coupled receptors, activated by the endogenous monoamine histamine, and classified into H1, H2, H3 and H4 receptors. Researchers can save up to 50% on histamine H1, H2, H3 and H4 receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.