Novel tool for studying GPCR desensitization
An exclusive from Hello Bio, Cmpd101 is a novel, potent, selective G-protein coupled receptor kinase 2 and 3 inhibitor (IC50 values are 35, 290 nM and 125 µM at GRK2, GRK3 and GRK5 respectively). Selective over other kinases. Can be used to study roles of GRK2/3 in GPCR desensitization...Read more
Metabotropic glutamate receptors are G-protein coupled receptors, classified into Group I (mGlu1, mGlu5), Group II (mGlu2, mGlu3), and Group III (mGlu4, mGlu6, mGlu7, mGlu8) receptors. Researchers can save 50% on metabotropic glutamate receptor agonists, antagonists, positive allosteric modulators (PAMs) and negative allosteric modulators (NAMs) from Hello Bio - they are up to half the price of other suppliers.