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Nuclear hormone

Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.

  1. Ciglitazone(HB2551)

    Description:

    Selective PPARγ agonist

    Purity :

    >99%

    Pack: Price: Qty:
    25mg
    $331
  2. Corticosterone

    Corticosterone(HB2808)

    Description:

    Endogenous gluococorticoid. MR and GR agonist.

    Purity :

    >99%

    Pack: Price: Qty:
    100mg
    $74
  3. Description:

    Orphan nuclear receptor DAF-12 ligand

    Purity :

    >95%

    Pack: Price: Qty:
    100μg
    $220
  4. Daidzein

    Daidzein(HB2488)

    Description:

    Estrogen receptors (ER) agonist. Phytoestrogen.

    Purity :

    >98%

    Pack: Price: Qty:
    50mg
    $82
  5. Dexamethasone

    Dexamethasone(HB2521)

    Description:

    Synthetic glucocorticoid. Induces hMSC differentiation.

    Purity :

    >98%

    Pack: Price: Qty:
    100mg
    $45
    1g
    $204
  6. Dexamethasone (water-soluble)
    Description:

    Synthetic glucocorticoid with potent anti-inflammatory actions. Induces hMSC differentiation. Water soluble and suitable for cell culture.

    Purity :

    >98%

    Pack: Price: Qty:
    100mg
    $72
  7. DPN

    DPN(HB2489)

    Description:

    Selective ERβ estrogen receptor agonist

    Purity :

    >99%

    Pack: Price: Qty:
    10mg
    $86
    50mg
    $375
  8. DY131

    DY131(HB2491)

    Description:

    Novel selective estrogen-related receptor ERRβ and ERRγ agonist

    Purity :

    >99%

    Pack: Price: Qty:
    10mg
    $103
    50mg
    $354
  9. EC 23

    EC 23(HB2592)

    Description:

    Synthetic retinoid. Induces neural differentiation of hESCs.

    Purity :

    >99%

    Pack: Price: Qty:
    5mg
    $80
    25mg
    $326
  10. 6-ECDCA

    6-ECDCA(HB3731)

    Description:

    Potent and selective FXR agonist

    Purity :

    >95%

    Pack: Price: Qty:
    25mg
    $267
  11. Ecdysone

    Ecdysone(HB3881)

    Description:

    Ecdysone receptor (EcR) agonist

    Purity :

    >95%

    Pack: Price: Qty:
    5mg
    $157
  12. Eplerenone

    Eplerenone(HB2527)

    Description:

    Selective mineralcorticoid receptor antagonist

    Purity :

    >99%

    Pack: Price: Qty:
    10mg
    $119
    50mg
    $451
  13. 17 β-Estradiol

    17 β-Estradiol(HB2494)

    Description:

    Estrogen receptor (ER) agonist

    Purity :

    >98%

    Pack: Price: Qty:
    100mg
    $34
  14. 17 α-Estradiol

    17 α-Estradiol(HB2493)

    Description:

    Estrogen receptor (ER) ligand. Non-feminizing estrogen.

    Purity :

    >96%

    Pack: Price: Qty:
    50mg
    $59
  15. FH 535

    FH 535(HB0288)

    Description:

    Wnt/β-catenin inhibitor and PPARγ/δ antagonist.

    Purity :

    >99%

    Pack: Price: Qty:
    50mg
    $352
  16. Fluticasone propionate
    Description:

    Selective glucocorticoid receptor agonist

    Pack: Price: Qty:
    10mg
    $164
    25mg
    $328
    100mg
    $983
  17. Genistein

    Genistein(HB2775)

    Description:

    Protein tyrosine kinase inhibitor and PPARγ agonist. Phytoestrogen.

    Purity :

    >98%

    Pack: Price: Qty:
    10mg
    $49
    50mg
    $136
  18. GW1929

    GW1929(HB3921)

    Description:

    Potent, subtype-selective PPARγ agonist

    Purity :

    >98%

    Pack: Price: Qty:
    25mg
    $455
  19. 20-Hydroxyecdysone
    Description:

    Ecdysone receptor (EcR) agonist. More potent than Ecdysone.

    Purity :

    >95%

    Pack: Price: Qty:
    50mg
    $403
  20. ICI 182,780 (Fulvestrant)
    Description:

    Estrogen receptor (ER) antagonist and high affinity GPER agonist

    Purity :

    >99%

    Pack: Price: Qty:
    1mg
    $75
    10mg
    $146
    50mg
    $571
  21. Mifepristone

    Mifepristone(HB2783)

    Description:

    Potent glucocorticoid and progesterone receptor antagonist

    Purity :

    >99%

    Pack: Price: Qty:
    100mg
    $75
  22. Muristerone A

    Muristerone A(HB3985)

    Description:

    Ecdysone receptor (EcR) agonist. Apoptosis inducer.

    Purity :

    >95%

    Pack: Price: Qty:
    1mg
    $152
  23. PHTPP

    PHTPP(HB2503)

    Description:

    Selective ERβ estrogen receptor antagonist

    Purity :

    >99%

    Pack: Price: Qty:
    10mg
    $146
    50mg
    $571
  24. Pifithrin-α hydrobromide
    Description:

    p53 inhibitor and Aryl hydrocarbon receptor agonist. Supresses ESC self renewal.

    Purity :

    >98%

    Pack: Price: Qty:
    10mg
    $110
  25. Pioglitazone hydrochloride
    Description:

    Selective PPARγ agonist

    Purity :

    >99%

    Pack: Price: Qty:
    10mg
    $59
    50mg
    $216
  26. Pioglitazone

    Pioglitazone(HB4139)

    Description:

    Selective PPARγ agonist

    Purity :

    >98%

    Pack: Price: Qty:
    5mg
    $36
    25mg
    $115
  27. Ponasterone A(HB4033)

    Description:

    Ecdysone receptor (EcR) agonist

    Purity :

    >95%

    Pack: Price: Qty:
    5mg
    $190
    25mg
    $753
  28. PPT

    PPT(HB2499)

    Description:

    Selective ERα estrogen receptor agonist

    Purity :

    >99%

    Pack: Price: Qty:
    5mg
    $65
    10mg
    $129
    25mg
    $258
  29. Raloxifene hydrochloride
    Description:

    Selective estrogen receptor modulator

    Purity :

    >98%

    Pack: Price: Qty:
    50mg
    $75
  30. Rosiglitazone

    Rosiglitazone(HB2556)

    Description:

    Potent and selective PPARγ agonist. Promotes adipocyte differentiation and enhances NPC proliferation.

    Purity :

    >99%

    Pack: Price: Qty:
    25mg
    $59
    100mg
    $157
  31. Rosiglitazone maleate
    Description:

    Potent and selective PPARγ agonist; antidiabetic agent.

    Purity :

    >98%

    Pack: Price: Qty:
    10mg
    $80
    50mg
    $274
  32. Spironolactone(HB2799)

    Description:

    Mineralocorticoid and androgen receptor antagonist

    Purity :

    >98%

    Pack: Price: Qty:
    50mg
    $59
  33. Stigmasterol

    Stigmasterol(HB4095)

    Description:

    Phytosterol with anticancer and many other biological actions. Farnesoid X receptor antagonist.

    Purity :

    >95%

    Pack: Price: Qty:
    5g
    $171
  34. Tamoxifen

    Tamoxifen(HB0601)

    Description:

    Estrogen receptor antagonist/ partial agonist

    Purity :

    >99%

    Pack: Price: Qty:
    100mg
    $52
  35. Tamoxifen Citrate
    Description:

    Estrogen receptor antagonist/ partial agonist

    Purity :

    >99%

    Pack: Price: Qty:
    500mg
    $42
    1g
    $84
    5g
    $338
  36. Troglitazone

    Troglitazone(HB2559)

    Description:

    Potent, selective PPARγ agonist. Inhibits hematopoietic cell line growth.

    Purity :

    >97%

    Pack: Price: Qty:
    25mg
    $220
  37. Zearalenone(HB2517)

    Description:

    Estrogen receptor agonist

    Purity :

    >98%

    Pack: Price: Qty:
    25mg
    $128