Nuclear hormone

Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.

  1. Ecdysone(HB3881)

    Description:

    Ecdysone receptor (EcR) agonist

    Purity :

    >95%

    Ecdysone
    Pack: Price: Qty:
    5mg
    $157
  2. Eplerenone(HB2527)

    Description:

    Selective mineralcorticoid receptor antagonist

    Purity :

    >99%

    Eplerenone
    Pack: Price: Qty:
    10mg
    $119
    50mg
    $451
  3. Description:

    Estrogen receptor (ER) agonist

    Purity :

    >98%

    17 β-Estradiol
    Pack: Price: Qty:
    100mg
    $59
  4. Description:

    Estrogen receptor (ER) ligand. Non-feminizing estrogen.

    Purity :

    >96%

    17 α-Estradiol
    Pack: Price: Qty:
    50mg
    $59
  5. FH 535(HB0288)

    Description:

    Wnt/β-catenin inhibitor and PPARγ/δ antagonist.

    Purity :

    >99%

    FH 535
    Pack: Price: Qty:
    50mg
    $352
  6. Description:

    Selective glucocorticoid receptor agonist

    Fluticasone propionate
    Pack: Price: Qty:
    10mg
    $164
    25mg
    $328
    100mg
    $983
  7. Genistein(HB2775)

    Description:

    Protein tyrosine kinase inhibitor and PPARγ agonist. Phytoestrogen.

    Purity :

    >98%

    Genistein
    Pack: Price: Qty:
    10mg
    $49
    50mg
    $136
  8. GW1929(HB3921)

    Description:

    Potent, subtype-selective PPARγ agonist

    Purity :

    >98%

    GW1929
    Pack: Price: Qty:
    25mg
    $455
  9. Description:

    Ecdysone receptor (EcR) agonist. More potent than Ecdysone.

    Purity :

    >95%

    20-Hydroxyecdysone
    Pack: Price: Qty:
    50mg
    $403
  10. Description:

    Estrogen receptor (ER) antagonist and high affinity GPER agonist

    Purity :

    >99%

    ICI 182,780 (Fulvestrant)
    Pack: Price: Qty:
    1mg
    $75
    10mg
    $146
    50mg
    $571