Nuclear hormone

Nuclear hormone receptors (nuclear receptors) are specialised transcription factors which bind to specific sequences of DNA of particular target genes. They regulate transcription of these target genes in response to a variety of endogenous ligands. Nuclear receptors are classified into two major subfamilies: steroid and non-steroid hormone receptors. Steroid hormone receptors include receptors for estrogen (ER), androgen, glucocorticoid, mineralocorticoid and progesterone. Examples of non-steroid hormone receptors include thyroid receptors, retinoic acid receptors and peroxisome proliferator-activated receptors (PPAR). Researchers can save up to 50% on nuclear hormone receptor agonists, antagonists and modulators from Hello Bio - they are up to half the price of other suppliers.

  1. Ciglitazone(HB2551)

    Description:

    Selective PPARγ agonist

    Purity :

    >99%

    Pack: Price: Qty:
    25mg
    $331
  2. Description:

    Endogenous gluococorticoid. MR and GR agonist.

    Purity :

    >99%

    Corticosterone
    Pack: Price: Qty:
    100mg
    $74
  3. Description:

    Orphan nuclear receptor DAF-12 ligand

    Purity :

    >95%

    Pack: Price: Qty:
    100μg
    $220
  4. Daidzein(HB2488)

    Description:

    Estrogen receptors (ER) agonist. Phytoestrogen.

    Purity :

    >98%

    Daidzein
    Pack: Price: Qty:
    50mg
    $82
  5. Description:

    Synthetic glucocorticoid. Induces hMSC differentiation.

    Purity :

    >98%

    Dexamethasone
    Pack: Price: Qty:
    100mg
    $45
    1g
    $204
  6. Description:

    Synthetic glucocorticoid with potent anti-inflammatory actions. Induces hMSC differentiation. Water soluble and suitable for cell culture.

    Purity :

    >98%

    Dexamethasone (water-soluble)
    Pack: Price: Qty:
    100mg
    $72
  7. DPN(HB2489)

    Description:

    Selective ERβ estrogen receptor agonist

    Purity :

    >99%

    DPN
    Pack: Price: Qty:
    10mg
    $86
    50mg
    $375
  8. DY131(HB2491)

    Description:

    Novel selective estrogen-related receptor ERRβ and ERRγ agonist

    Purity :

    >99%

    DY131
    Pack: Price: Qty:
    10mg
    $103
    50mg
    $354
  9. EC 23(HB2592)

    Description:

    Synthetic retinoid. Induces neural differentiation of hESCs.

    Purity :

    >99%

    EC 23
    Pack: Price: Qty:
    5mg
    $80
    25mg
    $326
  10. 6-ECDCA(HB3731)

    Description:

    Potent and selective FXR agonist

    Purity :

    >95%

    6-ECDCA
    Pack: Price: Qty:
    25mg
    $267
  11. Ecdysone(HB3881)

    Description:

    Ecdysone receptor (EcR) agonist

    Purity :

    >95%

    Ecdysone
    Pack: Price: Qty:
    5mg
    $157
  12. Eplerenone(HB2527)

    Description:

    Selective mineralcorticoid receptor antagonist

    Purity :

    >99%

    Eplerenone
    Pack: Price: Qty:
    10mg
    $119
    50mg
    $451
  13. Description:

    Estrogen receptor (ER) agonist

    Purity :

    >98%

    17 β-Estradiol
    Pack: Price: Qty:
    100mg
    $59
  14. Description:

    Estrogen receptor (ER) ligand. Non-feminizing estrogen.

    Purity :

    >96%

    17 α-Estradiol
    Pack: Price: Qty:
    50mg
    $59
  15. FH 535(HB0288)

    Description:

    Wnt/β-catenin inhibitor and PPARγ/δ antagonist.

    Purity :

    >99%

    FH 535
    Pack: Price: Qty:
    50mg
    $352
  16. Description:

    Selective glucocorticoid receptor agonist

    Fluticasone propionate
    Pack: Price: Qty:
    10mg
    $164
    25mg
    $328
    100mg
    $983
  17. Genistein(HB2775)

    Description:

    Protein tyrosine kinase inhibitor and PPARγ agonist. Phytoestrogen.

    Purity :

    >98%

    Genistein
    Pack: Price: Qty:
    10mg
    $49
    50mg
    $136
  18. GW1929(HB3921)

    Description:

    Potent, subtype-selective PPARγ agonist

    Purity :

    >98%

    GW1929
    Pack: Price: Qty:
    25mg
    $455
  19. Description:

    Ecdysone receptor (EcR) agonist. More potent than Ecdysone.

    Purity :

    >95%

    20-Hydroxyecdysone
    Pack: Price: Qty:
    50mg
    $403
  20. Description:

    Estrogen receptor (ER) antagonist and high affinity GPER agonist

    Purity :

    >99%

    ICI 182,780 (Fulvestrant)
    Pack: Price: Qty:
    1mg
    $75
    10mg
    $146
    50mg
    $571
  21. Mifepristone(HB2783)

    Description:

    Potent glucocorticoid and progesterone receptor antagonist

    Purity :

    >99%

    Mifepristone
    Pack: Price: Qty:
    100mg
    $75
  22. Description:

    Ecdysone receptor (EcR) agonist. Apoptosis inducer.

    Purity :

    >95%

    Muristerone A
    Pack: Price: Qty:
    1mg
    $152
  23. PHTPP(HB2503)

    Description:

    Selective ERβ estrogen receptor antagonist

    Purity :

    >99%

    PHTPP
    Pack: Price: Qty:
    10mg
    $146
    50mg
    $571
  24. Description:

    p53 inhibitor and Aryl hydrocarbon receptor agonist. Supresses ESC self renewal.

    Purity :

    >98%

    Pifithrin-α hydrobromide
    Pack: Price: Qty:
    10mg
    $110
  25. Description:

    Selective PPARγ agonist

    Purity :

    >99%

    Pioglitazone hydrochloride
    Pack: Price: Qty:
    10mg
    $59
    50mg
    $216
  26. Pioglitazone(HB4139)

    Description:

    Selective PPARγ agonist

    Purity :

    >98%

    Pioglitazone
    Pack: Price: Qty:
    5mg
    $36
    25mg
    $115
  27. Description:

    Ecdysone receptor (EcR) agonist

    Purity :

    >95%

    Pack: Price: Qty:
    5mg
    $190
    25mg
    $753
  28. PPT(HB2499)

    Description:

    Selective ERα estrogen receptor agonist

    Purity :

    >99%

    PPT
    Pack: Price: Qty:
    5mg
    $65
    10mg
    $129
    25mg
    $258
  29. Description:

    Selective estrogen receptor modulator

    Purity :

    >98%

    Raloxifene hydrochloride
    Pack: Price: Qty:
    50mg
    $75
  30. Description:

    Potent and selective PPARγ agonist. Promotes adipocyte differentiation and enhances NPC proliferation.

    Purity :

    >99%

    Rosiglitazone
    Pack: Price: Qty:
    25mg
    $59
    100mg
    $157
  31. Description:

    Potent and selective PPARγ agonist; antidiabetic agent.

    Purity :

    >98%

    Rosiglitazone maleate
    Pack: Price: Qty:
    10mg
    $80
    50mg
    $274
  32. Description:

    Mineralocorticoid and androgen receptor antagonist

    Purity :

    >98%

    Pack: Price: Qty:
    50mg
    $59
  33. Stigmasterol(HB4095)

    Description:

    Phytosterol with anticancer and many other biological actions. Farnesoid X receptor antagonist.

    Purity :

    >95%

    Stigmasterol
    Pack: Price: Qty:
    5g
    $171
  34. Tamoxifen(HB0601)

    Description:

    Estrogen receptor antagonist/ partial agonist

    Purity :

    >99%

    Tamoxifen
    Pack: Price: Qty:
    100mg
    $52
  35. Description:

    Estrogen receptor antagonist/ partial agonist

    Purity :

    >99%

    Tamoxifen Citrate
    Pack: Price: Qty:
    500mg
    $42
    1g
    $84
    5g
    $338
  36. Troglitazone(HB2559)

    Description:

    Potent, selective PPARγ agonist. Inhibits hematopoietic cell line growth.

    Purity :

    >97%

    Troglitazone
    Pack: Price: Qty:
    25mg
    $220
  37. Zearalenone(HB2517)

    Description:

    Estrogen receptor agonist

    Purity :

    >98%

    Pack: Price: Qty:
    25mg
    $128