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Antagonists & inhibitors

An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.

  1. 2-APB

    2-APB(HB1208)

    Description:

    IP3 receptor and store-operated channels (SOC) channel antagonist

    Pack: Price: Qty:
    10mg
    $41
    50mg
    $136
  2. 7BIO(HB3732)

    Description:

    Aurora B and C kinase inhibitor

    Purity :

    >99%

    Pack: Price: Qty:
    10mg
    $132
    50mg
    $532
  3. A-7 hydrochloride
    Description:

    Potent, cell-permeable calmodulin (CaM) antagonist

    Pack: Price: Qty:
    25mg
    $247
  4. A 803467

    A 803467(HB1007)

    Description:

    Potent, selective Nav1.8 channel inhibitor

    Purity :

    >98%

    Pack: Price: Qty:
    50mg
    $352
  5. A 83-01

    A 83-01(HB3218)

    Description:

    Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human induced pluripotent stem cell (hiPSC) self renewal.

    Purity :

    >98%

    Pack: Price: Qty:
    5mg
    $49
    25mg
    $220
  6. A 967079

    A 967079(HB1156)

    Description:

    Potent, selective TRPA1 channel blocker

    Purity :

    >98%

    Pack: Price: Qty:
    5mg
    $68
    10mg
    $102
    25mg
    $204
    50mg
    $409
  7. AACOCF3(HB2354)

    Description:

    Selective cPLA2 inhibitor

    Pack: Price: Qty:
    50mg
    $416
  8. 17-AAG(HB3599)

    Description:

    Selective Hsp90 inhibitor. Also protects neuroprogenitor cells against apoptosis.

    Purity :

    >98%

    Pack: Price: Qty:
    1mg
    $91
  9. Acetildenafil

    Acetildenafil(HB0103)

    Description:

    Sildenafil analog

    Purity :

    >98%

    Pack: Price: Qty:
    25mg
    $844
  10. Actinomycin D(HB1477)

    Description:

    RNA polymerase inhibitor

    Purity :

    >98%

    Pack: Price: Qty:
    5mg
    $46
    10mg
    $76
    25mg
    $157
    100mg
    $686