Antagonists & inhibitors

An antagonist is a drug or chemical that reduces the effect of an agonist. Competitive antagonists bind to the same site on a receptor as the agonist but do not activate it - thereby blocking the action of the agonist. Non-competitive antagonists block the action of the agonist by binding to a different site on the receptor (an allosteric or non-agonist site). A reversible antagonist binds non-covalently and can be washed out. An irreversible antagonist binds covalently and cannot be displaced by either competing ligands or washing. Inhibitors are drugs that can bind to a protein, such as an enzyme and decrease its activity. Researchers can save up to 50% on competitive antagonists, non-competitive antagonists, reversible and irreversible antagonists, and inhibitors from Hello Bio - they are up to half the price of other suppliers.

  1. UCPH-102(HB6130)

    Description:

    Selective EAAT1 inhibitor

    Purity :

    >98%

    UCPH-102
    Pack: Price: Qty:
    10mg
    $109
  2. Description:

    Dopamine release inhibitor

    Pack: Price: Qty:
    10mg
    $115
    50mg
    $434
  3. 7BIO(HB3732)

    Description:

    Aurora B and C kinase inhibitor

    Purity :

    >99%

    Pack: Price: Qty:
    10mg
    $132
    50mg
    $532
  4. A 484954(HB0093)

    Description:

    Potent, selective eEF-2K / CaMKIII inhibitor

    Purity :

    >98%

    A 484954
    Pack: Price: Qty:
    100mg
    $1,083
  5. Description:

    Potent, cell-permeable calmodulin (CaM) antagonist

    A-7 hydrochloride
    Pack: Price: Qty:
    25mg
    $247
  6. A 803467(HB1007)

    Description:

    Potent, selective Nav1.8 channel inhibitor

    Purity :

    >98%

    A 803467
    Pack: Price: Qty:
    50mg
    $352
  7. A 83-01(HB3218)

    Description:

    Selective TGF-βRI (ALK5), ALK4 and ALK7 inhibitor. Maintains human induced pluripotent stem cell (hiPSC) self renewal.

    Purity :

    >98%

    A 83-01
    Pack: Price: Qty:
    5mg
    $87
    25mg
    $305
  8. A 967079(HB1156)

    Description:

    Potent, selective TRPA1 channel blocker

    Purity :

    >98%

    A 967079
    Pack: Price: Qty:
    5mg
    $68
    10mg
    $102
    25mg
    $204
    50mg
    $409
  9. AACOCF3(HB2354)

    Description:

    Selective cPLA2 inhibitor

    Pack: Price: Qty:
    50mg
    $416
  10. 17-AAG(HB3599)

    Description:

    Selective Hsp90 inhibitor. Also protects neuroprogenitor cells against apoptosis.

    Purity :

    >98%

    Pack: Price: Qty:
    1mg
    $91
  11. Description:

    Sildenafil analog

    Purity :

    >98%

    Acetildenafil
    Pack: Price: Qty:
    25mg
    $844
  12. Description:

    RNA polymerase inhibitor

    Purity :

    >98%

    Pack: Price: Qty:
    5mg
    $46
    10mg
    $76
    100mg
    $686
    25mg
    $157
  13. Actinonin(HB3737)

    Description:

    Broad metalloprotease inhibitor

    Purity :

    >97%

    Pack: Price: Qty:
    25mg
    $361
  14. AF-DX 116(HB1501)

    Description:

    Selective, competitive M2 receptor antagonist

    Purity :

    >98%

    AF-DX 116
    Pack: Price: Qty:
    10mg
    $185
    50mg
    $700
  15. AG 490(HB1424)

    Description:

    Selective EGF receptor tyrosine kinase inhibitor

    Purity :

    >99%

    Pack: Price: Qty:
    50mg
    $332
  16. Agistatin B(HB3744)

    Description:

    Cholesterol biosynthesis inhibitor

    Purity :

    >98%

    Pack: Price: Qty:
    5mg
    $361
  17. Agistatin D(HB3745)

    Description:

    Cholesterol biosynthesis inhibitor. Analog of agistatin A.

    Purity :

    >98%

    Pack: Price: Qty:
    5mg
    $361
  18. AK-7(HB3747)

    Description:

    Brain-permeable SIRT2 (sirtuin 2) inhibitor

    Purity :

    >98%

    Pack: Price: Qty:
    25mg
    $342
  19. Aloeresin A(HB3749)

    Description:

    α-Glucosidase inhibitor. Aloesin metabolite.

    Purity :

    >97%

    Pack: Price: Qty:
    500μg
    $123
  20. Description:

    α7 subtype selective nAChR antagonist

    Purity :

    >99%

    Pack: Price: Qty:
    1mg
    $140
  21. Description:

    Non-selective β-adrenoceptor antagonist. Also a 5-HT1A receptor antagonist.

    Purity :

    >99%

    Pack: Price: Qty:
    10mg
    $71
  22. Description:

    Potent CDK1 inhibitor. Also shows activity at GSK-3β

    Purity :

    >98%

    Pack: Price: Qty:
    5mg
    $267
  23. Altenusin(HB3755)

    Description:

    Non-competitive, specific neutral sphingomyelinase (N-SMase) inhibitor.

    Purity :

    >97%

    Pack: Price: Qty:
    1mg
    $129
    5mg
    $436
  24. AM251(HB2776)

    Description:

    Potent, selective CB1 receptor antagonist / inverse agonist

    Purity :

    >98%

    Pack: Price: Qty:
    1mg
    $41
    10mg
    $87
    50mg
    $366
  25. AM 404(HB1174)

    Description:

    Selective, competitive carrier-mediated anandamide transport inhibitor

    Purity :

    >98%

    AM 404
    Pack: Price: Qty:
    10mg
    $64
    50mg
    $254
  26. Description:

    Non-competitive NMDA receptor antagonist

    Purity :

    >98%

    Amantadine hydrochloride
    Pack: Price: Qty:
    1g
    $15
    5g
    $25
  27. Description:

    Competitive aminopeptidase (AP) inhibitor

    Purity :

    >98%

    Pack: Price: Qty:
    5mg
    $144
  28. Amauromine(HB3758)

    Description:

    Potent and selective CB1 receptor antagonist

    Purity :

    >95%

    Pack: Price: Qty:
    1mg
    $144
  29. Description:

    Potent, selective CXCR4 antagonist. Mobilizes hematopoietic stem cells.

    AMD 3100 octahydrochloride
    Pack: Price: Qty:
    10mg
    $107
  30. AMG 9810(HB1188)

    Description:

    Potent, selective, competitive TRPV1 channel antagonist

    Purity :

    >98%

    AMG 9810
    Pack: Price: Qty:
    50mg
    $450
  31. Amidepsine A(HB3761)

    Description:

    Diacylglycerol acyltransferase (DGAT) inhibitor

    Purity :

    >95%

    Pack: Price: Qty:
    1mg
    $238
    2.5mg
    $474
  32. Amidepsine D(HB3762)

    Description:

    Diacylglycerol acyltransferase (DGAT) inhibitor

    Purity :

    >95%

    Pack: Price: Qty:
    1mg
    $238
    2.5mg
    $474
  33. Description:

    Ribosome-borne protein folding activity (RPFA) inhibitor

    Purity :

    >99%

    Pack: Price: Qty:
    5mg
    $157
  34. Description:

    NOS inhibitor

    Purity :

    >98%

    Pack: Price: Qty:
    100mg
    $51
  35. Description:

    Ribosome-borne protein folding activity (RPFA) inhibitor

    Purity :

    >97%

    Pack: Price: Qty:
    5mg
    $129
  36. Amisulpride(HB1879)

    Description:

    Potent, selective dopamine D2 and D3 receptor antagonist. Atypical antipsychotic.

    Purity :

    >98%

    Pack: Price: Qty:
    50mg
    $93
  37. Description:

    Serotonin/norepinephrine reuptake inhibitor (SNRI)

    Purity :

    >99%

    Pack: Price: Qty:
    1g
    $86
  38. Description:

    L-type calcium channel blocker

    Purity :

    >99%

    Amlodipine besylate
    Pack: Price: Qty:
    50mg
    $75
  39. Description:

    TRPM8 channel blocker

    Purity :

    >99%

    AMTB hydrochloride
    Pack: Price: Qty:
    5mg
    $67
    25mg
    $264
  40. Description:

    Non-competitive HAT inhibitor

    Purity :

    >97%

    Anacardic acid
    Pack: Price: Qty:
    5mg
    $48
    10mg
    $75
  41. Andrastin A(HB3763)

    Description:

    Protein farnesyltransferase (PFTase) inhibitor

    Purity :

    >95%

    Pack: Price: Qty:
    1mg
    $257
  42. AP 18(HB1157)

    Description:

    TRPA1 channel antagonist

    Purity :

    >98%

    AP 18
    Pack: Price: Qty:
    25mg
    $232
  43. DL-AP4(HB0249)

    Description:

    Broad spectrum glutamate antagonist

    Purity :

    >98%

    DL-AP4
    Pack: Price: Qty:
    50mg
    $33
  44. D-AP5(HB0225)

    Reviews:
    Description:

    Selective, competitive NMDA receptor antagonist

    Purity :

    >99%

    D-AP5 inhibition of NMDA receptor mediated EPSCs
    Pack: Price: Qty:
    1mg
    $37
    10mg
    $82
    50mg
    $346
    100mg
    $476
    50mM (add 1ml water)
    $91
    100mM (add 1ml water)
    $164
  45. DL-AP5(HB0251)

    Description:

    Competitive NMDA receptor antagonist

    Purity :

    >99%

    DL-AP5 inhibition of NMDA receptor mediated EPSCs
    Pack: Price: Qty:
    10mg
    $41
    50mg
    $162
  46. Description:

    Competitive NMDA receptor antagonist. Sodium salt.

    Purity :

    >98%

    DL-AP5 sodium inhibition of evoked NMDAR meditaed EPSCs
    Pack: Price: Qty:
    10mg
    $54
    50mg
    $209
  47. Apamin(HB1051)

    Description:

    Potent, selective KCa2 channel subfamily inhibitor

    Apamin
    Pack: Price: Qty:
    500μg
    $160
    1mg
    $236
    2.5mg
    $474
  48. Description:

    DNA polymerase α and δ inhibitor

    Purity :

    >98%

    Pack: Price: Qty:
    5mg
    $212
    25mg
    $697
  49. Apicidin(HB1384)

    Description:

    Potent HDAC inhibitor

    Purity :

    >98%

    Apicidin
    Pack: Price: Qty:
    10mg
    $581
    5mg
    $389
  50. Apigenin(HB0117)

    Description:

    PKC inhibitor

    Purity :

    >98%

    Apigenin
    Pack: Price: Qty:
    100mg
    $291