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Prostaglandin E2

(HB3460)
Data

Product overview

  • Name
    Prostaglandin E2
  • Short description
    Endogenous prostanoid. Induces hematopoietic stem cell proliferation.
  • Biological description
    Endogenous prostanoid (Kd values are ~1-10 nM at EP1, EP2, EP3 and EP4. Shows many biological actions and modulates various pathological and physiological activities. Induces hematopoietic stem cell (HSC) proliferation.
  • Alternative names
    Dinoprostone | PGE2
  • Biological action
    Activator
  • Purity
    >98%
  • Citations

Properties

  • Chemical name
    (5Z,11α,13E,15S)-11,15-Dihydroxy-9-o xo-prosta-5,13-dien-1oic acid
  • Molecular Weight
    352.47
  • Chemical structure
    Prostaglandin E2 |  [363-24-6]
  • Molecular Formula
    C20H32O5
  • CAS Number
    363-24-6

Storing and Using Your Product

  • Storage instructions
    -20°C
  • Solubility overview
    soluble in DMSO (100mM) or ethanol (45mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Prostaglandin E2

  • The multiple faces of prostaglandin E2 G-protein coupled receptor signaling during the dendritic cell life cycle.

    De Keijzer et al (2013) Int J Mol Sci 14(4) : 6542-55
    PubMedID: 23528886
  • Roles of prostaglandin E2 in cardiovascular diseases.

    Suzuki et al (2011) Int Heart J 52(5) : 266-9
    PubMedID: 22008433
  • Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis.

    North et al (2007) Nature 447(7147) : 1007-11
    PubMedID: 17581586
  • International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes.

    Coleman et al (1994) Pharmacol Rev 46(2) : 205-29
    PubMedID: 7938166
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