PTP Inhibitor IV

(HB0539)

Product overview

  • Name
    PTP Inhibitor IV
  • Short description
    PTP inhibitor
  • Biological description
    Protein tyrosine phosphatase (PTP) inhibitor. Attenuates oligodendrocyte maturation. Impairs the differentiation of endothelial cells. Shows anti-angiogenic actions.
  • Biological action
    Inhibitor
  • Purity
    >95%
  • Citations

Properties

  • Molecular Weight
    608.6
  • Molecular Formula
    C26H26F6N2O4S2

Storing and Using Your Product

  • Storage instructions
    +4°C
  • Solubility overview
    soluble in DMSO (10mg/ml) or ACN.
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for PTP Inhibitor IV

  • PTP inhibitor IV protects JNK kinase activity by inhibiting dual-specificity phosphatase 14 (DUSP14).

    Park JE et al (2009) Biochem Biophys Res Commun 387(4) : 795-9.
    PubMedID: 19646420
  • Phosphatase inhibitors with anti-angiogenic effect in vitro.

    Sylvest L et al (2010) APMIS 118(1) : 49-59.
    PubMedID: 20041871
  • SHP-2 promotes the maturation of oligodendrocyte precursor cells through Akt and ERK1/2 signaling in vitro.

    Liu X et al (2011) PLoS One 6(6) : e21058.
    PubMedID: 21701583

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