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Product overview

  • Name
  • Short description
    Potent HDAC inhibitor
  • Biological description
    Potent histone deacetylase (HDAC) inhibitor (ID50 = 100 nM for HDAC1). Increases p21/WAF expression and shows growth inhibitory actions in cancer cells.
  • Alternative names
    Suberoyl-3-aminopyridineamide hydroxamic acid
  • Biological action
  • Purity
  • Citations


  • Chemical name
    N-Hydroxy-N'-3-pyridinyloctanediamid e
  • Molecular Weight
  • Chemical structure
    Pyroxamide  [382180-17-8]
  • Molecular Formula
  • CAS Number

Storing and Using Your Product

  • Storage instructions
  • Solubility overview
    soluble in DMSO (100mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Pyroxamide

  • Inhibition of transformed cell growth and induction of cellular differentiation by pyroxamide, an inhibitor of histone deacetylase.

    Butler LM et al (2001) Clin Cancer Res 7(4) : 962-70.
    PubMedID: 11309347
  • Histone deacetylase inhibitors induce growth suppression and cell death in human rhabdomyosarcoma in vitro.

    Kutko MC et al (2003) Clin Cancer Res 9(15) : 5749-55.
    PubMedID: 14654560
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