Q-VD-OPh

(HB4048)

Product overview

  • Name
    Q-VD-OPh
  • Short description
    Cell permeable, irreversible and non-toxic pan-caspase inhibitor
  • Biological description
    Cell permeable, irreversible and non-toxic non-FMK pan-caspase inhibitor with improved potency, stability and toxicity over Z-VAD-FMK. Does not cross-react with cathepsins nor calpains. Non-toxic due to the 2,6-difluorophenoxy methyl (OPh) group. The peptide is not O-methylated to reduce hydrophobicity and to facilitate use in aqueous media. Inhibits ICE-family protease/caspase processing, leading to apoptosis and autophagy induction. Decreases proteasome activity. Used in apoptosis and inflammasome studies.
  • Purity
    >95%
  • Our products in action

Properties

  • Chemical name
    N-(2-Quinolyl)-L-valyl-L-aspartyl-(2,6-difluorophenoxy) methylketone
  • Molecular Weight
    513.5
  • Chemical structure
    Q-VD-OPh [1135695-98-5 (anhydrous)]
  • CAS Number
    1135695-98-5 (anhydrous)
  • InChiKey
    OOBJCYKITXPCNS-AKRCKQFNSA-N
  • Appearance
    White solid

Storing and Using Your Product

  • Storage instructions
    +4°C
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Reviews & Product Guides