Quercetin

(HB0542)

Product overview

  • Name
    Quercetin
  • Short description
    Enzyme inhibitor
  • Biological description
    Enzyme inhibitor. Inhibits tyrosine protein kinase, phosphodiesterase and phospholipase A2. Inhibits L-type voltage-gated calcium channel inward currents and increases voltage-gated K+ channel currents. Shows antioxidant, neuroprotective, antidepressant, anxiolytic, antitumor, anti-asthma and vasodilator actions.
  • Biological action
    Inhibitor
  • Purity
    >98%
  • Citations

Properties

  • Chemical name
    2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one
  • Molecular Weight
    302.24
  • Chemical structure
    Quercetin  [117-39-5]
  • Molecular Formula
    C15H10O7
  • CAS Number
    117-39-5
  • PubChem identifier
    5280343
  • SMILES
    C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Solubility overview
    soluble in methanol or DMSO
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Quercetin

  • Tyrosine protein kinase activity in the DMBA-induced rat mammary tumor: inhibition by quercetin.

    Levy J et al (1984) Biochem Biophys Res Commun 123(3) : 1227-33.
    PubMedID: 6091650
  • Enhancement of voltage-gated K+ channels and depression of voltage-gated Ca2+ channels are involved in quercetin-induced vasorelaxation in rat coronary artery.

    Hou X et al (2014) Planta Med 80(6) : 465-72.
    PubMedID: 24710898
  • Quercetin acutely relaxes airway smooth muscle and potentiates β-agonist-induced relaxation via dual phosphodiesterase inhibition of PLCβ and PDE4.

    Townsend EA et al (2013) Am J Physiol Lung Cell Mol Physiol 305(5) : L396-403.
    PubMedID: 23873842
  • Quercetin as an inhibitor of snake venom secretory phospholipase A2.

    Cotrim CA et al (2011) Chem Biol Interact 189(1-2) : 9-16.
    PubMedID: 21056032

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