In my cart

You have no items in your shopping cart.

(R)-(-)-Rolipram

(HB2898)
Data

Product overview

  • Name
    (R)-(-)-Rolipram
  • Short description
    Potent, selective PDE4 inhibitor. Enantiomer of Rolipram.
  • Biological description
    Enantiomer of Rolipram. Potent and selective phosphodiesterase PDE4 inhibitor (IC50 values are 0.22 and 0.29 µM for membrane-bound PDE4 and cytosolic PDE4 respectively).
  • Biological action
    Inhibitor
  • Citations

Properties

  • Chemical name
    4R)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one
  • Molecular Weight
    275.35
  • Chemical structure
    (R)-(-)-Rolipram [85416-75-7]
  • Molecular Formula
    C16H21NO3
  • CAS Number
    85416-75-7
  • PubChem identifier
    448055
  • SMILES
    COC1=C(C=C(C=C1)[C@H]2CC(=O)NC2)OC3CCCC3
  • InChi
    InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18)/t12-/m0/s1
  • InChiKey
    HJORMJIFDVBMOB-LBPRGKRZSA-N
  • MDL number
    MFCD03093860

Storing and Using Your Product

  • Storage instructions
    Room temperature
  • Solubility overview
    Soluble in DMSO (100 mM) and ethanol (100 mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Support & Resources

Reviews & Product Guides