Product overview

Name (R)-(-)-Rolipram
Purity >98%
Description Potent, selective PDE4 inhibitor. Enantiomer of Rolipram.
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Biological Data

Biological description Enantiomer of Rolipram. Potent and selective phosphodiesterase PDE4 inhibitor (IC50 values are 0.22 and 0.29 µM for membrane-bound PDE4 and cytosolic PDE4 respectively).

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in DMSO (100 mM) and ethanol (100 mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >98%
Chemical name 4R)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one
Molecular Weight 275.35
Chemical structure (R)-(-)-Rolipram [85416-75-7] Chemical Structure
Molecular Formula C16H21NO3
CAS Number 85416-75-7
PubChem identifier 448055
SMILES COC1=C(C=C(C=C1)[C@H]2CC(=O)NC2)OC3CCCC3
InChi InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18)/t12-/m0/s1
InChiKey HJORMJIFDVBMOB-LBPRGKRZSA-N
MDL number MFCD03093860