Great quality by half the price of other suppliers. We have been using riluzole from regular suppliers for many years. Now, we have tested Riluzole from Hello Bio and this has worked fantastic. Compound activity is comparable to the previous one, but the price is almost half of it. Also, the user experience working with them is easy and fast. I definitely recommend this compound. Verified customer, University of Vigo
Na+ channel blocker. Increases glutamate uptake, inhibits glutamate release and inhibits GABA uptake. Non-competitive NMDA receptor and Protein kinase C (PKC) inhibitor and a TREK-1 K2P channel activator. Shows neuroprotective, anxiolytic, anticonvulsant and anesthetic actions. Shows actions against motorneuron disease.
Solubility & Handling
Storage instructions
Room temperature
Solubility overview
Soluble in DMSO (100 mM), and in ethanol (100 mM)
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Riluzole blocks persistent Na+ and Ca2+ currents and modulates release of glutamate via presynaptic NMDA receptors on neonatal rat hypoglossal motoneurons in vitro.
Lamanauskas N et al (2008) Eur J Neurosci 27(10) : 2501-14.
These publications cite the use of Riluzole purchased from Hello Bio:
Activation of TREK currents by riluzole in three subgroups of cultured mouse nodose ganglion neurons
Fernández-Fernández D, Cadaveira-Mosquera A, Rueda-Ruzafa L, Herrera-Pérez S, Veale EL, Reboreda A, Mathie A, Lamas JA. (2018) Plos ONE 13(6) : e0199282
![Riluzole [1744-22-5] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb6093.png "Riluzole [1744-22-5]")
Understanding purity and quality - a guide for life scientists
