Risperidone

(HB1740)

Product overview

  • Name
    Risperidone
  • Short description
    5-HT2A and D2 receptor antagonist
  • Biological description
    5-HT2A and D2 receptor antagonist (Ki values are 0.4, 1.3, 6.7 and 7.5 nM at 5-HT2A , D2, D3 and D5 receptors respectively). Also shows affinity for α1 and α2 and H1 receptors. Atypical antipsychotic. Active in vivo.
  • Alternative names
    R 64 766
  • Biological action
    Antagonist
  • Purity
    >99%
  • Citations

Properties

  • Chemical name
    3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-me thyl-4H-pyrido[1,2-a]pyrimidin-4-one
  • Molecular Weight
    410.48
  • Chemical structure
    Risperidone  [106266-06-2]
  • Molecular Formula
    C23H27FN4O2
  • CAS Number
    106266-06-2

Storing and Using Your Product

  • Storage instructions
    +4°C
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Risperidone

  • Biochemical profile of risperidone, a new antipsychotic.

    Leysen JE et al (1988) J Pharmacol Exp Ther 247(2) : 661-70.
    PubMedID: 2460616
  • Antipsychotic drugs: importance of dopamine receptors for mechanisms of therapeutic actions and side effects.

    Strange PG (2001) Pharmacol Rev 53(1) : 119-33.
    PubMedID: 11171942
  • Long-term effects of olanzapine, risperidone, and quetiapine on dopamine receptor types in regions of rat brain: implications for antipsychotic drug treatment.

    Tarazi FI et al (2001) J Pharmacol Exp Ther 297(2) : 711-7.
    PubMedID: 11303062

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