Rosiglitazone
(HB2556)- Data
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Data
Product overview
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Name
Rosiglitazone
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Short description
Potent and selective PPARγ agonist. Promotes adipocyte differentiation and enhances NPC proliferation.
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Biological description
Potent and selective PPARγ agonist. Potent insulin sensitizing agent which binds PPAR receptors to fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance and shows antidiabetic, hypoglycemic and anti-inflammatory action. Also promotes mesenchymal stem cells (MSCs) adipocyte differentiation and enhances endogenous neural progenitor cells (NPCs) proliferation.
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Biological action
Agonist
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Purity
>99%
- Citations
Properties
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Chemical name
5-[[4-[2-(Methyl-2-pyridinylamino)e thoxy]phenyl]methyl]-2,4-thiazolidinedione
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Molecular Weight
357.43
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Chemical structure
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Molecular Formula
C18H19N3O3S
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CAS Number
122320-73-4
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PubChem identifier
77999
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SMILES
CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3
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InChi
InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,15H,10-12H2,1H3,(H,20,22,23)
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InChiKey
YASAKCUCGLMORW-UHFFFAOYSA-N
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MDL number
MFCD00871760
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Appearance
White to off-white powder
Storing and Using Your Product
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Storage instructions
+4°C
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Solubility overview
Soluble in 0.1M HCl (100 mM), and in DMSO (100 mM)
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Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
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