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Rosiglitazone

(HB2556)
Data

Product overview

  • Name
    Rosiglitazone
  • Short description
    Potent and selective PPARγ agonist. Promotes adipocyte differentiation and enhances NPC proliferation.
  • Biological description
    Potent and selective PPARγ agonist. Potent insulin sensitizing agent which binds PPAR receptors to fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance and shows antidiabetic, hypoglycemic and anti-inflammatory action. Also promotes mesenchymal stem cells (MSCs) adipocyte differentiation and enhances endogenous neural progenitor cells (NPCs) proliferation.
  • Biological action
    Agonist
  • Purity
    >99%
  • Citations

Properties

  • Chemical name
    5-[[4-[2-(Methyl-2-pyridinylamino)e thoxy]phenyl]methyl]-2,4-thiazolidinedione
  • Molecular Weight
    357.43
  • Chemical structure
    Rosiglitazone [122320-73-4]
  • Molecular Formula
    C18H19N3O3S
  • CAS Number
    122320-73-4
  • PubChem identifier
    77999
  • SMILES
    CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3
  • InChi
    InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,15H,10-12H2,1H3,(H,20,22,23)
  • InChiKey
    YASAKCUCGLMORW-UHFFFAOYSA-N
  • MDL number
    MFCD00871760
  • Appearance
    White to off-white powder

Storing and Using Your Product

  • Storage instructions
    +4°C
  • Solubility overview
    Soluble in 0.1M HCl (100 mM), and in DMSO (100 mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
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