Rufinamide

(HB1039)

Product overview

  • Name
    Rufinamide
  • Short description
    Na+ channel blocker
  • Biological description
    Na+ channel blocker. Shows higher selectivity for Nav1.7. Also mGluR5 antagonist. A novel triazole derivative. Prolongs sodium channel inactivation. Displays anticonvulsant and antiepileptic actions.
  • Biological action
    Blocker
  • Purity
    >99%
  • Our products in action

Properties

  • Chemical name
    1-[(2,6-Difluorophenyl)methyl]-1H-1,2,3-triazole-4-carboxamide
  • Molecular Weight
    238.19
  • Chemical structure
    Rufinamide  [106308-44-5]
  • Molecular Formula
    C10H8F2N4O
  • CAS Number
    106308-44-5

Storing and Using Your Product

  • Storage instructions
    room temperature (desiccate)
  • Solubility overview
    soluble in DMSO (100mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Rufinamide

  • Rufinamide.

    Arroyo S (2007) Neurotherapeutics 4(1) : 155-62.
    PubMedID: 17199032
  • Rufinamide attenuates mechanical allodynia in a model of neuropathic pain in the mouse and stabilizes voltage-gated sodium channel inactivated state.

    Suter MR et al (2013) Anesthesiology 118(1) : 160-72.
    PubMedID: 23221868
  • Rufinamide.

    Deeks ED et al (2006) CNS Drugs 20(9) : 751-60
    PubMedID: 16953653

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