(S)-MCPG sodium salt
(HB6112)
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Code: HB0026
Pack: 10mg,50mg,10mM (add 1ml water)
Code: HB0431
Pack: 10mg,50mg
Code: HB0225
Pack: 1mg,10mg,50mg,100mg,50mM (add 1ml water),100mM (add 1ml water)
(S)-MCPG sodium salt
(HB6112)- Data
- Support & Resources
Product overview
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Name
(S)-MCPG sodium salt
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Short description
Non-selective group I and II mGluR antagonist. Water soluble sodium salt.
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Biological description
Non-selective group I and II mGluR antagonist. Water soluble sodium salt.
Active enantiomer of (R,S)-MCPG.
Displays slight activity at mGlu8 receptor but none at mGlu4 receptor.Inhibits MF-LTP (mossy fiber long term potentiation) and blocks induction of LTP in CA1 of rat hippocampus.
(S)-MCPG and (R,S)-MCPG sodium salt also available. -
Biological action
Antagonist
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Purity
>99%
- Citations
Properties
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Chemical name
(S)-α-Methyl-4-carboxyphenylglycine sodium salt
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Molecular Weight
231.18
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Chemical structure
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Molecular Formula
C10H10NNaO4
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CAS Number
150145-89-4
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Source
Syntheitc
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Appearance
White solid
Storing and Using Your Product
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Storage instructions
Room temperature
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Solubility overview
Soluble in water (100mM)
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Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for (S)-MCPG sodium salt
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Structure-activity relationships for a series of phenylglycine derivatives acting at metabotropic glutamate receptors (mGluRs).
Bedingfield JS et al (1995) Br J Pharmacol 116(8) : 3323-9.PubMedID: 8719814 -
Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes.
Sekiyama N et al (1996) Br J Pharmacol 117(7) : 1493-503.PubMedID: 8730745 -
Pharmacological agents acting at subtypes of metabotropic glutamate receptors.
Schoepp DD et al (1999) Neuropharmacology 38(10) : 1431-76.PubMedID: 10530808
Reviews & Product Guides
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