(S)-MCPG sodium salt

(HB6112)

Pack	Price	Qty
10mg	$150
50mg	$595

(HB6112)

Data

Product overview

Name
(S)-MCPG sodium salt
Short description
Non-selective group I and II mGluR antagonist. Water soluble sodium salt.
Biological description
Non-selective group I and II mGluR antagonist. Water soluble sodium salt.
Active enantiomer of (R,S)-MCPG.

Displays slight activity at mGlu₈ receptor but none at mGlu₄ receptor.
Inhibits MF-LTP (mossy fiber long term potentiation) and blocks induction of LTP in CA1 of rat hippocampus.

(S)-MCPG and (R,S)-MCPG sodium salt also available.
Biological action
Antagonist
Purity
>99%
Citations
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Storage instructions
Room temperature
Solubility overview
Soluble in water (100mM)
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Structure-activity relationships for a series of phenylglycine derivatives acting at metabotropic glutamate receptors (mGluRs).
Bedingfield JS et al (1995) Br J Pharmacol 116(8) : 3323-9.
PubMedID: 8719814
Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes.
Sekiyama N et al (1996) Br J Pharmacol 117(7) : 1493-503.
PubMedID: 8730745
Pharmacological agents acting at subtypes of metabotropic glutamate receptors.
Schoepp DD et al (1999) Neuropharmacology 38(10) : 1431-76.
PubMedID: 10530808

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