Product overview

Name (S)-Roscovitine
Purity >99%
Description Potent, selective CDK1 inhibitor
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Biological Data

Biological description (S)-enantiomer of (R)-roscovitine. Potent selective cyclin-dependent kinase 1 (CDK1) inhibitor. Potential neuroprotectant for stroke. Crosses the blood brain barrier. Inhibits CDK5, consequently blocking hypoxia-induced apoptosis in neurons. Potential anti-inflammatory compound. Potential antidiabetic compound.

Solubility & Handling

Storage instructions +4°C
Solubility overview

Soluble in DMSO (100 mg/ml)

Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >99%
Chemical name

2-(S)-(1-Ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine

Molecular Weight 354.5
Chemical structure (S)-Roscovitine [186692-45-5] Chemical Structure
Molecular Formula C19H26N6O
CAS Number 186692-45-5
PubChem identifier 6603989
SMILES CC[C@@H](CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CC=CC=C3
InChi InChI=1S/C19H26N6O/c1-4-15(11-26)22-19-23-17(20-10-14-8-6-5-7-9-14)16-18(24-19)25(12-21-16)13(2)3/h5-9,12-13,15,26H,4,10-11H2,1-3H3,(H2,20,22,23,24)/t15-/m0/s1
InChiKey BTIHMVBBUGXLCJ-HNNXBMFYSA-N
Appearance White to off-white solid