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Product overview

  • Name
  • Short description
    Selective D2-like receptor antagonist. Active enantiomer.
  • Biological description
    Selective D2-like receptor antagonist. Active enantiomer. (Ki values are 2.5 and 8 nM at D2, D3, >1000 nM at D4, D5 and D1 receptors respectively). Antipsychotic. Active in vivo.
  • Biological action
  • Purity
  • Citations


  • Chemical name
  • Molecular Weight
  • Chemical structure
    (S)-(-)-Sulpiride  [23672-07-3]
  • Molecular Formula
  • CAS Number

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for (S)-(-)-Sulpiride

  • Antipsychotic drugs: importance of dopamine receptors for mechanisms of therapeutic actions and side effects.

    Strange PG (2001) Pharmacol Rev 53(1) : 119-33.
    PubMedID: 11171942
  • Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1.

    Sunahara RK et al (1991) Nature 350(6319) : 614-9.
    PubMedID: 1826762
  • Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation.

    Dong E et al (2008) Proc Natl Acad Sci U S A 105(36) : 13614-9.
    PubMedID: 18757738
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