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Data

Product overview

  • Name
    SAG
  • Short description
    Cell permeable Sonic hedgehog (Shh) agonist and Smo agonist. Enhances neuronal differentiation.
  • Biological description
    Potent, cell-permeable Smo receptor agonist (Kd = 59 nM) and hedgehog (Hh) signaling activator. Counteracts cyclopamine inhibition of Smo. Acts as an Smo activator at low concentrations and an inhibitor at high concentrations. Also enhances neuronal differentiation of iPSC into dopaminergic neurons.
  • Biological action
    Agonist
  • Purity
    >98%
  • Citations

Properties

  • Chemical name
    N-Methyl-N'-(3-pyridinylbenzyl)-N'-(3-chlorobenzo[b]thiophene-2-carbonyl)-1,4-diaminocyclohexane
  • Molecular Weight
    490.1
  • Chemical structure
    SAG [912545-86-9]
  • CAS Number
    912545-86-9
  • InChiKey
    VFSUUTYAEQOIMW-YHBQERECSA-N
  • Appearance
    Off-white to light yellow powder

Storing and Using Your Product

  • Storage instructions
    +4°C
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
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