In my cart

You have no items in your shopping cart.

Data

Product overview

  • Name
    Salvinorin A
  • Short description
    Potent, selective κ opioid receptor (KOP) agonist
  • Biological description
    Potent, selective κ opioid receptor (KOP) agonist (Ki = 4.3 nM). Isolated from Salvia divinorum. Only non-nitrogenous κ opioid agonist, lacks chemical features associated with opiate ligand activity. Also acts as an allosteric modulator of μ opioid receptors. Shows psychoactive activity. Active in vivo.

    Not for sale in the US or Canada
  • Alternative names
    Divinorin A, SALA
  • Biological action
    Antagonist
  • Citations

Properties

  • Chemical name
    (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(Acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester
  • Molecular Weight
    432.5
  • Chemical structure
    Salvinorin A [83729-01-5]
  • Molecular Formula
    C23H28O8 · 0.25H2O
  • CAS Number
    83729-01-5
  • PubChem identifier
    128563
  • SMILES
    CC(=O)O[C@H]1C[C@H]([C@@]2(CC[C@H]3C(=O)O[C@@H](C[C@@]3([C@H]2C1=O)C)C4=COC=C4)C)C(=O)OC
  • Source
    Extracted from Salvia divinorum
  • InChi
    InChI=1S/C23H28O8/c1-12(24)30-16-9-15(20(26)28-4)22(2)7-5-14-21(27)31-17(13-6-8-29-11-13)10-23(14,3)19(22)18(16)25/h6,8,11,14-17,19H,5,7,9-10H2,1-4H3/t14-,15-,16-,17-,19-,22-,23-/m0/s1
  • InChiKey
    OBSYBRPAKCASQB-AGQYDFLVSA-N
  • MDL number
    MFCD05664742
  • Appearance
    White solid

Storing and Using Your Product

  • Storage instructions
    -20 °C
  • Solubility overview
    Soluble in ethanol (20 mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Salvinorin A

  • Salvinorin A: allosteric interactions at the mu-opioid receptor.

    Rothman et al (2007) J Pharmacol Exp Ther 320(2) : 801-10
    PubMedID: 17060492
  • A unique binding epitope for salvinorin A, a non-nitrogenous kappa opioid receptor agonist.

    Kane et al (2006) FEBS J 273(9) : 1966-74
    PubMedID: 16640560
  • Salvinorin A: the "magic mint" hallucinogen finds a molecular target in the kappa opioid receptor.

    Sheffler and Roth (2003) Trends Pharmacol Sci. 24(3) : 107-9
    PubMedID: 12628350
Support & Resources

Reviews & Product Guides