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Product overview

  • Name
    Salvinorin A
  • Short description
    Potent, selective κ opioid receptor (KOP) agonist
  • Biological description
    Potent, selective κ opioid receptor (KOP) agonist (Ki = 4.3 nM). Isolated from Salvia divinorum. Only non-nitrogenous κ opioid agonist, lacks chemical features associated with opiate ligand activity. Also acts as an allosteric modulator of μ opioid receptors. Shows psychoactive activity. Active in vivo.

    Not for sale in the US or Canada
  • Alternative names
    Divinorin A, SALA
  • Biological action
  • Citations


  • Chemical name
    (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(Acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester
  • Molecular Weight
  • Chemical structure
    Salvinorin A [83729-01-5]
  • Molecular Formula
    C23H28O8 · 0.25H2O
  • CAS Number
  • PubChem identifier
  • Source
    Extracted from Salvia divinorum
  • InChi
  • InChiKey
  • MDL number
  • Appearance
    White solid

Storing and Using Your Product

  • Storage instructions
    -20 °C
  • Solubility overview
    Soluble in ethanol (20 mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Salvinorin A

  • Salvinorin A: allosteric interactions at the mu-opioid receptor.

    Rothman et al (2007) J Pharmacol Exp Ther 320(2) : 801-10
    PubMedID: 17060492
  • A unique binding epitope for salvinorin A, a non-nitrogenous kappa opioid receptor agonist.

    Kane et al (2006) FEBS J 273(9) : 1966-74
    PubMedID: 16640560
  • Salvinorin A: the "magic mint" hallucinogen finds a molecular target in the kappa opioid receptor.

    Sheffler and Roth (2003) Trends Pharmacol Sci. 24(3) : 107-9
    PubMedID: 12628350
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