Product overview

Name SB 224289 hydrochloride
Purity >95%
Description Selective 5-HT1B receptor antagonist
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Biological Data

Biological description Selective 5-HT1B receptor antagonist (pKi = 8.2). Displays > 60-fold selectivity over 5-HT1D, 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A and 5-HT2C receptors. Active in vivo.

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in DMSO (10mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Purity >95%
Chemical name 1'-Methyl-5-[[2'-methyl-4'-(5-methyl-1 ,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6, 7-tetrahydrospiro[furo[2,3-f]indole-3,4'-piperidine hydrochloride
Molecular Weight 557.09
Molecular Formula C32H32N4O3.HCl
CAS Number 180084-26-8
PubChem identifier 11226716
SMILES O=C(C5=CC=C(C6=CC=C(C7=NOC(C)=N7)C=C6C)C=C5)N2C1=CC3=C(OCC43CCN(CC4)C)C=C1CC2.Cl
InChiKey GKGKBZYMDILCOF-UHFFFAOYSA-N