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Product overview

  • Name
  • Short description
    Potent HDAC inhibitor
  • Biological description
    Potent histone deacetylase (HDAC) inhibitor (IC50 values are 0.64, 1.4, 14.5, 34 and 607 nM for HDAC1, 8, 6 and 3 respectively). Increases expression of estrogen receptor α in breast cancer cells and reactivates latent HIV infection. Shows growth inhibitory, anti-cancer and neuroprotective actions.
  • Biological action
  • Purity
  • Citations


  • Chemical name
    N-Hydroxy-1,3-dioxo-1H-benz[de]isoq uinoline-2(3H)-hexanamide
  • Molecular Weight
  • Chemical structure
    Scriptaid  [287383-59-9]
  • Molecular Formula
  • CAS Number

Storing and Using Your Product

  • Storage instructions
    -20°C (desiccate)
  • Solubility overview
    soluble in DMSO (100mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Scriptaid

  • A novel histone deacetylase inhibitor, scriptaid, enhances expression of functional estrogen receptor alpha (ER) in ER negative human breast cancer cells in combination with 5-aza 2'-deoxycytidine.

    Keen JC et al (2003) Breast Cancer Res Treat 81(3) : 177-86.
    PubMedID: 14620913
  • Inhibitors of histone deacetylases: correlation between isoform specificity and reactivation of HIV type 1 (HIV-1) from latently infected cells.

    Huber K et al (2011) J Biol Chem 286(25) : 22211-8.
    PubMedID: 21531716
  • Scriptaid, a novel histone deacetylase inhibitor, protects against traumatic brain injury via modulation of PTEN and AKT pathway : scriptaid protects against TBI via AKT.

    Wang G et al (2013) Neurotherapeutics 10(1) : 124-42.
    PubMedID: 23132328
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