Product overview

Name SKF 97541
Alternative names CGP 35024
Purity >98%
Description Potent GABAB receptor agonist
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Biological Data

Biological description Potent GABAB receptor agonist. Evokes hyperpolarizations in septal neurones (EC50 = 50 nM). Shows antidepressant actions. Blood-brain barrier permeable.

Solubility & Handling

Storage instructions

Room temperature (desiccate)

Solubility overview Soluble in water (100mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >98%
Chemical name 3-Aminopropyl(methyl)phosphinic acid
Molecular Weight 137.12
Chemical structure SKF 97541  [127729-35-5] Chemical Structure
Molecular Formula C4H12NO2P
CAS Number 127729-35-5
PubChem identifier 5230
SMILES NCCCP(O)(C)=O
Source Synthetic
InChiKey NHVRIDDXGZPJTJ-UHFFFAOYSA-N
Appearance White solid

References for SKF 97541

References are publications that support the biological activity of the product
  • Effects of GABAB receptor ligands in animal tests of depression and anxiety.

    Frankowska M et al (2007) Pharmacol Rep 59(6) : 645-55.
  • Electrophysiological actions of GABAB agonists and antagonists in rat dorso-lateral septal neurones in vitro.

    Bon C et al (1996) Br J Pharmacol 118(4) : 961-7.
  • Electrophysiological characterization of potent agonists and antagonists at pre- and postsynaptic GABAB receptors on neurones in rat brain slices.

    Seabrook GR et al (1990) Br J Pharmacol 101(4) : 949-57.

3 Item(s)