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SL 0101-1


Product overview

  • Name
    SL 0101-1
  • Short description
    Selective p90 ribosomal S6 kinase inhibitor
  • Biological description
    Selective p90 ribosomal S6 kinase (RSK) inhibitor (IC50 = 89 nM for RSK2). Shows anti-proliferative actions against cancer cell lines.
  • Alternative names
  • Biological action
  • Purity
  • Citations


  • Chemical name
    3-[(3,4-Di-O-acetyl-6-deoxy-α-L-mannopyranosyl)oxy]-5,7-dihydro-2-(4-hydroxyphenyl)-4H -1benzopyran-4-one
  • Molecular Weight
  • Chemical structure
    SL 0101-1  [77307-50-7]
  • Molecular Formula
  • CAS Number

Storing and Using Your Product

  • Storage instructions
  • Solubility overview
    soluble in ethanol (20mM) or DMSO (10mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for SL 0101-1

  • Identification of the first specific inhibitor of p90 ribosomal S6 kinase (RSK) reveals an unexpected role for RSK in cancer cell proliferation.

    Smith JA et al (2005) Cancer Res 65(3) : 1027-34.
    PubMedID: 15705904
  • Inhibition of RSK/YB-1 signaling enhances the anti-cancer effect of enzalutamide in prostate cancer.

    Shiota M et al (2014) Prostate 74(9) : 959-69.
    PubMedID: 24740858
  • The selectivity of protein kinase inhibitors: a further update.

    Bain J et al (2007) Biochem J 408(3) : 297-315.
    PubMedID: 17850214
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