Product overview

  • Name
    SN 2
  • Short description
    Selective TRPML3 channel activator
  • Biological description
    Selective TRPML3 channel activator (EC50 = 1.13 µM). Also Increases intracellular Ca2+ concentrations.
  • Biological action
    Activator
  • Purity
    >98%
  • Our products in action

Properties

  • Chemical name
    3a,4,5,6,7,7a-Hexahydro-3-(2,4,6-trimethylphenyl)-4,7-methano-1,2-benzisoxazole
  • Molecular Weight
    255.35
  • Chemical structure
    SN 2  [823218-99-1]
  • Molecular Formula
    C17H21NO
  • CAS Number
    823218-99-1

Storing and Using Your Product

  • Storage instructions
    +4°C
  • Solubility overview
    soluble in DMSO (100mM) or ethanol (100mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for SN 2

  • Small molecule activators of TRPML3.

    Grimm C et al (2010) Chem Biol 17(2) : 135-48.
    PubMedID: 20189104
  • Genetic inactivation of Trpml3 does not lead to hearing and vestibular impairment in mice.

    Jörs S et al (2010) PLoS One 5(12) : e14317.
    PubMedID: 21179200

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