In my cart

You have no items in your shopping cart.

Splitomicin

(HB4091)
Data

Product overview

  • Name
    Splitomicin
  • Short description
    Potent,selective, cell permeable yeast NAD+-dependent HDAC Sir2p inhibitor
  • Biological description
    Potent, selective and cell permeable yeast NAD+-dependent histone deacetylase (HDAC) Sir2p inhibitor. Displays higher activity in vivo than in vitro. Sensitizes mammalian cells to a variety of DNA-damaging agents by abrogating Sir2p activity on p53. Acts by either altering or blocking access to the acetylated histone binding pocket. Shown to have diverse effects also in mammalian cells.
  • Purity
    >98%
  • Citations

Properties

  • Chemical name
    1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one
  • Molecular Weight
    198.2
  • Chemical structure
    Splitomicin [5690-03-9]
  • Molecular Formula
    C13H10O2
  • CAS Number
    09/03/5690
  • PubChem identifier
    5269
  • SMILES
    O=C1CCC2=C(O1)C=CC1=CC=CC=C21
  • InChiKey
    ISFPDBUKMJDAJH-UHFFFAOYSA-N
  • Appearance
    White to off-white solid

Storing and Using Your Product

  • Storage instructions
    +4°C
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
Support & Resources

Reviews & Product Guides