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Data

Product overview

  • Name
    TC-N 1752
  • Short description
    Potent, selective Nav1.7 inhibitor
  • Biological description
    Potent and selective Nav1.7 channel inhibitor (IC50 = 0.17 µM). Shows antinociceptive actions.
  • Alternative names
    Compound 52
  • Biological action
    Inhibitor
  • Purity
    >99%
  • Citations

Properties

  • Chemical name
    N-[2-Methyl-3-[[4-[4-[[4-(trifluoro methoxy)phenyl]methoxy]-1-piperidinyl]-1,3,5-triaz in-2-yl]amino]phenyl]acetamide
  • Molecular Weight
    516.52
  • Chemical structure
    TC-N 1752  [1211866-85-1]
  • Molecular Formula
    C25H27F3N6O3
  • CAS Number
    1211866-85-1

Storing and Using Your Product

  • Storage instructions
    +4°C
  • Solubility overview
    soluble in DMSO (100mM) or HCl (10mM, 1eq HCl)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for TC-N 1752

  • Identification of a potent, state-dependent inhibitor of Nav1.7 with oral efficacy in the formalin model of persistent pain.

    Bregman H et al (2011) J Med Chem 54(13) : 4427-45.
    PubMedID: 21634377
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