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Images
TC-N 1752 product vial image | Hello Bio
TC-N 1752 product vial image | Hello Bio
Biological Data
| Biological description | Potent and selective Nav1.7 channel inhibitor (IC50 = 0.17 µM). Shows antinociceptive actions. |
Solubility & Handling
| Storage instructions | +4°C |
| Solubility overview | Soluble in DMSO (100mM) or HCl (10mM, 1eq HCl) |
| Important | This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use. |
Chemical Data
| Chemical name | N-[2-Methyl-3-[[4-[4-[[4-(trifluoro methoxy)phenyl]methoxy]-1-piperidinyl]-1,3,5-triaz in-2-yl]amino]phenyl]acetamide |
| Chemical structure | ![TC-N 1752 [1211866-85-1] Chemical Structure](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAABCAQAAAC1HAwCAAAAC0lEQVR4nGP6zwAAAgcBApocMXEAAAAASUVORK5CYII= "TC-N 1752 [1211866-85-1]") |
| Molecular Formula | C25H27F3N6O3 |
| PubChem identifier | 53361524 |
| SMILES | CC(C(NC(C)=O)=CC=C4)=C4NC1=NC=NC(N2CCC(OCC3=CC=C(OC(F)(F)F)C=C3)CC2)=N1 |
| InChiKey | QLKAFHZJICDACE-UHFFFAOYSA-N |
References for TC-N 1752
References are publications that support the biological activity of the product
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Identification of a potent, state-dependent inhibitor of Nav1.7 with oral efficacy in the formalin model of persistent pain.
Bregman H et al (2011) J Med Chem 54(13) : 4427-45.
Potent, selective Nav1.7 inhibitor
![TC-N 1752 [1211866-85-1] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb1033.png "TC-N 1752 [1211866-85-1]")
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