TC-S 7003


Product overview

  • Name
    TC-S 7003
  • Short description
    Potent Lck inhibitor
  • Biological description
    Potent lymphocyte specific kinase (Lck) inhibitor. Inhibits Lck, Lyn, Src and Syk (IC50 values 7, 21, 42 and 200 nM respectively).
  • Biological action
  • Purity
  • Our products in action


  • Chemical name
  • Molecular Weight
  • Molecular Formula
  • CAS Number

Storing and Using Your Product

  • Storage instructions
  • Solubility overview
    soluble in DMSO (100mM, gentle warming) or ethanol (10mM, gentle warming)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for TC-S 7003

  • Structure-based design of novel 2-amino-6-phenyl-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as potent and orally active inhibitors of lymphocyte specific kinase (Lck): synthesis, SAR, and in vivo anti-inflammatory activity.

    Martin MW et al (2008) J Med Chem 51(6) : 1637-48.
    PubMedID: 18278858

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