The store will not work correctly in the case when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
Biological Data Biological description AT1 (Angiotensin II receptor type 1) antagonist / blocker (Ki = 3.7 nM). It is also a PPARγ partial agonist.
Shows anti-hypertensive effects.
Recently investigated as part of COVID-19 compound repurposing.
Solubility & Handling Solubility overview Soluble in DMSO (20mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use
Chemical Data Chemical name 2-(4-{[4-Methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl}phenyl)benzoic acid
Chemical structure
Molecular Formula C33 H30 N4 O2
SMILES O=C(O)c1ccccc1c2ccc(cc2)Cn3c4cc(cc(c4nc3CCC)C)c5nc6ccccc6n5C
InChi InChI=1S/C33H30N4O2/c1-4-9-30-35-31-21(2)18-24(32-34-27-12-7-8-13-28(27)36(32)3)19-29(31)37(30)20-22-14-16-23(17-15-22)25-10-5-6-11-26(25)33(38)39/h5-8,10-19H,4,9,20H2,1-3H3,(H,38,39)
InChiKey RMMXLENWKUUMAY-UHFFFAOYSA-N
References for Telmisartan References are publications that support the biological activity of the product
Telmisartan as tentative angiotensin receptor blocker therapeutic for COVID-19 Rothlin et al (2020) Drug Dev Res. 1l10 : 1002 6-Substituted benzimidazoles as new nonpeptide angiotensin II receptor antagonists: synthesis, biological activity, and structure-activity relationships Ries et al (1993) J Med Chem 36(25) : 4040-51 Pharmacological characterization of the novel nonpeptide angiotensin II receptor antagonist, BIBR 277 Wienen et al (1993) Br J Pharmacol. 110(1) : 245-52.
AT1 antagonist and PPARγ partial agonist
![Telmisartan [144701-48-4] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb2558_1.png "Telmisartan [144701-48-4]")
Understanding purity and quality - a guide for life scientists
