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Product overview

  • Name
  • Short description
    Cholesteryl ester transfer protein inhibitor
  • Biological description
    Cholesteryl ester transfer protein (CETP) inhibitor. Raises HDL in dyslipidemia, improves glucose homeostasis and insulin resistance. Inhibits vasodilation and increases aldosterone to show hypertensive actions.
  • Biological action
  • Purity
  • Citations


  • Chemical name
    (2R,4S)-4-[[[3,5-bis(Trifluoromethyl)phenyl]methyl](methoxycarbonyl)amino]-2-ethyl-6- (trifluoromethyl)-1,2,3,4-tetrahydroquinoline-1-carboxylic acid ethyl ester
  • Molecular Weight
  • Chemical structure
    Torcetrapib  [262352-17-0]
  • Molecular Formula
  • CAS Number

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Solubility overview
    soluble in DMSO (50mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Torcetrapib

  • Torcetrapib produces endothelial dysfunction independent of cholesteryl ester transfer protein inhibition.

    Connelly MA et al (2010) J Cardiovasc Pharmacol 55(5) : 459-68.
    PubMedID: 20051879
  • Raising HDL with CETP inhibitor torcetrapib improves glucose homeostasis in dyslipidemic and insulin resistant hamsters.

    Briand F et al (2014) Atherosclerosis 233(2) : 359-62.
    PubMedID: 24530763
  • Upregulating reverse cholesterol transport with cholesteryl ester transfer protein inhibition requires combination with the LDL-lowering drug berberine in dyslipidemic hamsters.

    Briand F et al (2013) Arterioscler Thromb Vasc Biol 33(1) : 13-23.
    PubMedID: 23139291
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