Non-ATP competitive Aurora A and B kinase inhibitor
Non-ATP competitive Aurora A and B kinase inhibitor (IC50 = 1.5, 7 and >10 µM at Aurora A, B, EGFR, FGFR, KDR and IGF1R respectively). Reduces localization of pAurora A on spindle microtubules (MTs), affects centrosome integrity, spindle formation and length and MT dynamics in interphase.
Storing and Using Your Product
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.