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Product overview

  • Name
  • Short description
    GlcNAc phosphotransferase inhibitor
  • Biological description
    GlcNAc phosphotransferase (GPT) inhibitor. Inhibits glycoprotein synthesis. Causes endoplasmic reticulum stress and apoptosis. Shows antibiotic and anticancer actions.
  • Biological action
  • Citations


  • Chemical name
    Tunicamycin from Streptomyces sp.
  • Molecular Weight
  • Chemical structure
    Tunicamycin  [11089-65-9]
  • Molecular Formula
    C39H64N4O16 (tunicamycin C, n=10)
  • CAS Number
  • Source
    Streptomyces sp
  • MDL number
  • Appearance
    Off-white solid

Storing and Using Your Product

  • Storage instructions
  • Solubility overview
    Soluble in DMSO (50mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Tunicamycin

  • Dipeptidyl petidase-IV inhibitor (gemigliptin) inhibits tunicamycin-induced endoplasmic reticulum stress, apoptosis and inflammation in H9c2 cardiomyocytes.

    Hwang HJ et al (2014) Mol Cell Endocrinol 392(1-2) : 1-7.
    PubMedID: 24813659
  • Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival.

    Ding WX et al (2007) J Biol Chem 282(7) : 4702-10.
    PubMedID: 17135238
  • Tunicamycin potentiates cisplatin anticancer efficacy through the DPAGT1/Akt/ABCG2 pathway in mouse Xenograft models of human hepatocellular carcinoma.

    Hou H et al (2013) Mol Cancer Ther 12(12) : 2874-84.
    PubMedID: 24130050
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