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Biological Data

Biological description Potent and selective FAAH inhibitor (IC50 values are 4.6 and 0.5 nM in rat brain memebrane and cortical neurons respectively). Causes an accumulation of anandamide. Shows little activity at various cannabinoid related targets. Displays antidepressant, antinociceptive, anxiolytic and analgesic effects.

Solubility & Handling

Storage instructions +4°C
Solubility overview Soluble in DMSO (50mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Chemical Data

Purity >99%
Chemical name Cyclohexylcarbamic acid 3'-(Aminocarbonyl)-[1,1'-biphenyl]-3- yl ester
Molecular Weight 338.4
Chemical structure URB 597 | [546141-08-6] Chemical Structure
Molecular Formula C20H22N2O3
CAS Number 546141-08-6
PubChem identifier 1383884
SMILES C1CCC(CC1)NC(=O)OC2=CC=CC(=C2)C3=CC(=CC=C3)C(=O)N
InChi InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)
InChiKey ROFVXGGUISEHAM-UHFFFAOYSA-N
MDL number MFCD05863934