Na+ channel activator. Binds to active channels and prevents the inactive state. Increases persistent sodium current and intracellular Ca2+. Increases reverse Na+ / Ca2+ exchange current, pump activity and exocytosis. Induces action potentials and extended membrane depolarization.
Solubility & Handling
Storage instructions
-20°C
Solubility overview
Soluble in DMSO (50mM)
Important
This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References are publications that support the biological activity of the product
[Involvement of veratridine-induced increase of reverse Na(+)/Ca(2+) exchange current in intracellular Ca(2+) overload and extension of action potential duration in rabbit ventricular myocytes].
Kong LH et al (2012) Sheng Li Xue Bao 64(4) : 433-43.
![Veratridine [71-62-5] Chemical Structure](https://hellobio.com/media/catalog/product//h/b/hb1006.png "Veratridine [71-62-5]")
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