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VU 0360223


Product overview

  • Name
    VU 0360223
  • Short description
    mGlu5 negative allosteric modulator
  • Biological description
    mGlu5 receptor negative allosteric modulator (IC50 = 61 nM). Exhibits little or no activity at mGlu1-4 and mGlu7-8 receptors. Blood-brain barrier permeable.
  • Biological action
  • Purity
  • Citations


  • Chemical name
  • Molecular Weight
  • Chemical structure
    VU 0360223  [1274859-33-4]
  • Molecular Formula
  • CAS Number

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Solubility overview
    soluble in DMSO (25mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for VU 0360223

  • (3-Cyano-5-fluorophenyl)biaryl negative allosteric modulators of mGlu(5): Discovery of a new tool compound with activity in the OSS mouse model of addiction.

    Lindsley CW et al (2011) ACS Chem Neurosci 2(8) : 471-482.
    PubMedID: 21927650
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