VU 0364439

(HB0639)

Product overview

  • Name
    VU 0364439
  • Short description
    Potent mGlu4 positive allosteric modulator
  • Biological description
    Potent mGlu4 receptor positive allosteric modulator (EC50 = 19.8 nM).
  • Biological action
    PAM
  • Purity
    >99%
  • Our products in action

Properties

  • Chemical name
    N-[3-Chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]-2-pyridinecarboxamide
  • Molecular Weight
    422.29
  • Chemical structure
    VU 0364439  [1246086-78-1]
  • Molecular Formula
    C18H13Cl2N3O3S
  • CAS Number
    1246086-78-1

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Solubility overview
    soluble in DMSO (100mM)

References for VU 0364439

  • Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS).

    Engers DW et al (2010) Bioorg Med Chem Lett 20(17) : 5175-8.
    PubMedID: 20667732