Product overview

Name W-5 hydrochloride
Alternative names W-5; W5
Purity >98%
Description Calmodulin (CaM) antagonist
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Biological Data

Biological description Calmodulin (CaM) antagonist. Reverses the inhibitory effect of insulin via dibutytyl cAMP. A chlorine-deficient inactive analogue of W-7.

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in DMSO (50mM) or water (10mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

Molarity

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Dilution

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Chemical Data

Purity >98%
Chemical name N-(6-Aminohexyl)-1-naphthalenesulfonamide hydrochloride
Molecular Weight 342.88
Chemical structure W-5 hydrochloride  [61714-25-8] Chemical Structure
Molecular Formula C16H22N2O2S.HCl
CAS Number 61714-25-8
PubChem identifier 173829
SMILES Cl.NCCCCCCNS(=O)(=O)C1=C2C=CC=CC2=CC=C1
InChiKey HOCSVIGHWPLMFC-UHFFFAOYSA-N

References for W-5 hydrochloride

References are publications that support the biological activity of the product
  • W-5 and quin 2-AM reverse the inhibitory effect of insulin on lipolysis due to dibutyryl cAMP.

    Goko H et al (1999) Diabetes Res Clin Pract 44(2) : 101-6.
  • Effect of calmodulin antagonists on auxin-induced elongation.

    Raghothama KG et al (1985) Plant Physiol 79(1) : 28-33.
  • N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation.

    Hidaka H et al (1981) Proc Natl Acad Sci U S A 78(7) : 4354-7.

3 Item(s)