Product overview

Name WAY 100635 maleate
Purity >99%
Description Potent 5-HT1A receptor antagonist. D4 receptor agonist.
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Biological Data

Biological description Potent 5-HT1A receptor antagonist (IC50 value = 2.2 nM). More than 100-fold selective for 5-HT1A compared with other 5-HT receptors. Also acts as an agonist at D4 receptor (IC50 value = 16 nM). Active in vivo.

Solubility & Handling

Storage instructions room temperature (desiccate)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >99%
Chemical name N-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinylcyclohexanecarboxamide maleate
Molecular Weight 538.64
Chemical structure WAY 100635 maleate  [634908-75-1] Chemical Structure
Molecular Formula C25H34N4O2.C4H4O4
CAS Number 634908-75-1
PubChem identifier 11957721
SMILES O=C(C4CCCCC4)N(C3=NC=CC=C3)CCN(CC2)CCN2C1=C(OC)C=CC=C1.O=C(\C=C/C(O)=O)O
InChiKey XIGAHNVCEFUYOV-BTJKTKAUSA-N

References for WAY 100635 maleate

References are publications that support the biological activity of the product
  • WAY 100635 produces discriminative stimulus effects in rats mediated by dopamine D(4) receptor activation.

    Marona-Lewicka D et al (2009) Behav Pharmacol 20(1) : 114-8.
  • WAY-100635 is a potent dopamine D4 receptor agonist.

    Chemel BR et al (2006) Psychopharmacology (Berl) 188(2) : 244-51.
  • A pharmacological profile of the selective silent 5-HT1A receptor antagonist, WAY-100635.

    Forster EA et al (1995) Eur J Pharmacol 281(1) : 81-8.

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