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Wedelolactone

(HB4124)
Data

Product overview

  • Name
    Wedelolactone
  • Short description
    Selective IKKα and IKKβ kinase activity inhibitor. NF-κB inhibitor.
  • Biological description
    Cell permeable, selective and irreversible IKKalpha and beta kinase activity inhibitor. NF-kappaB inhibitor. Blocks phosphorylation and degradation of IkappaBalpha. Antihepatotoxic. 5-Lipoxygenase (5-LOX) inhibitor. Anti-inflammatory. HIV-1 integrase inhibitor. Anticancer and antiproliferative compound. Modulates androgen receptor (AR) activation. Apoptosis inducer via downregulation of PKCepsilon. DNA topoisomerase IIalpha inhibitor. G protein-coupled receptor-35 (GPR35) agonist. Inhibits adipogenic differentiation of mesenchymal stem cells (hAMSCs) through ERK pathway. STAT1 protein dephosphorylation inhibitor. Antifibrotic.
  • Purity
    >98%
  • Citations

Properties

  • Chemical name
    7-Methoxy-5,11,12-trihydroxy-coumestan
  • Molecular Weight
    314.2
  • Chemical structure
    Wedelolactone [524-12-9]
  • CAS Number
    524-12-9
  • InChiKey
    XQDCKJKKMFWXGB-UHFFFAOYSA-N
  • Appearance
    Yellow to amber crystalline powder

Storing and Using Your Product

  • Storage instructions
    +4°C
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
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