Xanthurenic acid

(HB0659)

Product overview

  • Name
    Xanthurenic acid
  • Short description
    Endogenous group II mGlu agonist
  • Biological description
    Endogenous group II mGluR agonist. Displays apoptosis inducing properties and induces the exflagellation of Plasmodium microgametocytes.
  • Biological action
    Agonist
  • Purity
    >98%
  • Our products in action

Properties

  • Chemical name
    4,8-Dihydroxyquinoline-2-carboxylic acid
  • Molecular Weight
    205.17
  • Chemical structure
    Xanthurenic acid  [59-00-7]
  • Molecular Formula
    C10H7NO4
  • CAS Number
    59-00-7

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Solubility overview
    soluble in DMSO (100mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Xanthurenic acid

  • Actions of Xanthurenic acid, a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus.

    Copeland CS et al (2013) Neuropharmacology 66 : 133-42.
    PubMedID: 22491023
  • Pathological apoptosis by xanthurenic acid, a tryptophan metabolite: activation of cell caspases but not cytoskeleton breakdown.

    Malina HZ et al (2001) BMC Physiol 1 : 7
    PubMedID: 11459518
  • The tryptophan oxidation pathway in mosquitoes with emphasis on xanthurenic acid biosynthesis.

    Han Q et al (2007) J Insect Physiol 53(3) : 254-63.
    PubMedID: 17070835