Product overview

Name Xanthurenic acid
Purity >98%
Description Endogenous group II mGlu agonist
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Biological Data

Biological description Endogenous group II mGluR agonist. Displays apoptosis inducing properties and induces the exflagellation of Plasmodium microgametocytes.

Solubility & Handling

Storage instructions Room temperature
Solubility overview Soluble in DMSO (100mM)
Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

Calculators

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Dilution

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Chemical Data

Purity >98%
Chemical name 4,8-Dihydroxyquinoline-2-carboxylic acid
Molecular Weight 205.17
Chemical structure Xanthurenic acid  [59-00-7] Chemical Structure
Molecular Formula C10H7NO4
CAS Number 59-00-7
PubChem identifier 5699
SMILES OC1=C2C(C(O)=CC(C(O)=O)=N2)=CC=C1
InChiKey FBZONXHGGPHHIY-UHFFFAOYSA-N

References for Xanthurenic acid

References are publications that support the biological activity of the product
  • Actions of Xanthurenic acid, a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus.

    Copeland CS et al (2013) Neuropharmacology 66 : 133-42.
  • The tryptophan oxidation pathway in mosquitoes with emphasis on xanthurenic acid biosynthesis.

    Han Q et al (2007) J Insect Physiol 53(3) : 254-63.
  • Pathological apoptosis by xanthurenic acid, a tryptophan metabolite: activation of cell caspases but not cytoskeleton breakdown.

    Malina HZ et al (2001) BMC Physiol 1 : 7

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