Z-DQMD-FMK

(HB1283)

Product overview

  • Name
    Z-DQMD-FMK
  • Short description
    Cell permeable caspase 3 specific inhibitor
  • Biological description
    Cell permeable caspase 3 specific inhibitor. Attenuates β-catenin degradation but does not affect β-catenin and GSK-3β phosphorylation
  • Biological action
    Inhibitor
  • Citations

Properties

  • Chemical name
    Benzyloxycarbonyl-Asp(OMe)-Gln-Met-Asp(OMe)-fluoromethylketone
  • Molecular Weight
    685.72
  • Molecular Formula
    C29H40FN5O11S

Storing and Using Your Product

  • Storage instructions
    -20°C (desiccate)
  • Solubility overview
    soluble in DMSO (13.71mg/ml)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Z-DQMD-FMK

  • Inhibiting caspase-3 activity blocks beta-catenin degradation after focal ischemia in rat.

    Zhang H et al (2008) Neuroreport 19(8) : 821-4.
    PubMedID: 18463494
  • Photodynamic therapy in combination with talaporfin sodium induces mitochondrial apoptotic cell death accompanied with necrosis in glioma cells.

    Miki Y et al (2013) Biol Pharm Bull 36(2) : 215-21.
    PubMedID: 23196427

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